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Latest from Actorius

Explore the latest updates, research perspectives, announcements, and stories shaping our work.

ASCO 2023 | Actorius Innovations and Research
Jun 6, 2023

ASCO 2023: Effect of circulating tumor cells distribution in treatment naive and treated patients with advance stage breast cancer on disease burden.

A study of 417 breast cancer patients shows tracking circulating tumor cells (CTCs) effectively monitors therapy response and recurrence risk.

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ASCO 2023 | Actorius Innovations and Research
Jun 6, 2023

ASCO 2023: Circulating tumor cells (CTCs) detection and isolation in different subtypes of early-stage breast cancer patients from Bangladesh.

A trial found CTCs in 60% of early-stage breast cancer patients, notably all HER2-positive cases, linking them to tumor grade. Send the next!

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AACR 2023 | Actorius Innovations and Research
Apr 19, 2023

AACR 2023: Detection of PD-L1, HER2 and EGFR on circulating tumor cells in carcinoma patients.

CTC analysis in 134 patients successfully detected PD-L1, HER2, and EGFR, proving its value as a real-time guide for targeted therapies.

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Chemical tunability of advanced materials used in the fabrication of micro/nanobots
Apr 11, 2023

Manuscript: Chemical tunability of advanced materials used in the fabrication of micro/nanobots

Review on chemically tunable micro- and nanobots for targeted nanomedicine, highlighting AI materials, applications, and biosafety considerations.

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Economic times  | Actorius Innovations and Research
Mar 6, 2023

Pune start-up gets US patent for delivering drugs to site-specific organs

The patent was granted to Actorius Innovations and Research and its team that designed capsule shells using natural polymer to obtain a delayed release profile suitable for delivery of drugs to colon and rectum, said Dr Jayant Khandare, founder-director and Chief Scientific Officer of the start-up.

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TEDx Talk —  by Aravindan Vasudevan – CEO, Actorius Innovations and Research
Feb 28, 2023

TEDx Talk — Capturing cancer cells-Uncovering secrets for treatments by Aravindan Vasudevan – CEO, Actorius Innovations

Aravindan discusses innovative cancer research in early detection, precision medicine, tumor modeling, and liquid biopsy for advanced cancer insights.

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Actorius Patent
Feb 13, 2023

Devices and methods for recovering disease-causing toxic constituents in the blood

A cost-effective, high-efficiency nanosystem for rapid circulating tumor cell enumeration.

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AACR 2023 | Actorius Innovations and Research
Jan 15, 2023

AACR 2023: Abstract PR007: Comprehensive ctDNA profiling reveals potential metastatic genomic signatures in treatment-naive early-stage breast cancer patients

Comprehensive ctDNA profiling and CTC analysis in early-stage breast cancer identifies driver mutations to predict early metastasis.

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OncoDiscover | Actorius Innovations and Research
Aug 9, 20222

OncoDiscover Available in India | Dr. Jayant Khandare

OncoDiscover Available in India | Dr. Jayant Khandare

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OncoDiscover | Actorius Innovations and Research
Aug 28, 2022

Revolutionary Blood Test Detects Cancer Relapse Early | Dr. Jayant Khandare

Discover India's first approved, highly affordable blood test that detects cancer relapse and metastasis earlier than traditional CT or MRI scans. Developed by Dr. Jayant Khandare and clinically validated with Tata Memorial Hospital, this painless test catches circulating tumor cells before it's too late.

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OncoDiscover | Actorius Innovations and Research
Aug 9, 2022

OncoDiscover Lab Walkthrough

OncoDiscover Lab Walkthrough

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Dr. Nirmal Raut | Actorius Innovations and Research
Aug 9, 2022

Preventing Stage 4 Cancer: India’s Revolutionary Blood Test | Dr. Nirmal Raut

Leading oncologists discuss OncoDiscover, India's first indigenous CTC blood test. By detecting Circulating Tumor Cells post-treatment, this affordable "Made in India" innovation catches cancer relapse before it reaches incurable Stage 4, dramatically changing the landscape of cancer care.

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Dr. Jayant Khandare interview with Metro News Gujarat
Aug 9, 2022

Revolutionary OncoDiscover® Blood Test for Early Cancer Detection - Metro News Gujarat

Dr. Jayant Khandare interview with Metro News Gujarat

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Dr. Pankaj Chaturvedi | Actorius Innovations and Research
Aug 9, 2022

Made in India: The Low-Cost Blood Test Revolutionizing Cancer Care | Dr. Pankaj Chaturvedi

Dr. Pankaj Chaturvedi (Director, ACTREC) and Dr. Jayant Khandare discuss OncoDiscover, India's first indigenous CTC blood test. By detecting cancer relapse earlier than traditional scans, this groundbreaking "Made in India" technology drastically lowers patient costs and paves the way for future medical innovations.

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Preoperative CTC levels predict prognosis and survival in oral squamous cell carcinoma.
Jul 1, 2022

Manuscript: Circulating tumor cells as a predictor for poor prognostic factors and overall survival in treatment nay¨ve oral squamous cell carcinoma patients

Preoperative circulating tumor cell levels strongly correlate with metastasis, disease severity, and reduced survival in oral squamous cell carcinoma patients.

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ASCO 2022 | Actorius Innovations and Research
Jun 7, 2022

ASCO 2022: CTCs as a biomarker for monitoring: Disease progression, treatment response, and minimal residual disease.

Study of 127 patients shows CTCs are a dynamic biomarker for monitoring disease progression and therapy response in advanced epithelial cancers.

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ASCO. 2022 | Actorius Innovations and Research
Jun 7, 2022

ASCO 2022: Machine learning (ML)–enabled, circulating tumor cell–based classification of patients for non-prerequisite adjuvant therapy.

An XGBoost ML model using CTCs and clinical data achieved 84% accuracy in predicting the need for adjuvant therapy in 380 HNSCC patients.

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ASCO 2022 | Actorius Innovations and Research
Jun 7, 2022

ASCO 2022: Extracorporeal microchannel device to capture and eliminate circulating tumor cells from
cancer patient’s blood.

A 3D-printed G-EpCAM device successfully captured over 85% of CTCs with minimal hemolysis, offering a new way to stem metastatic progression.

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ASCO 2022 | Actorius Innovations and Research
Jun 7, 2022

ASCO 2022: A feasibility study of EMF (erlotinib+methotrexate+5-fluorouracil) regimen in recurrent HNSCC and role of CTCs in assessment of outcomes.

A phase II trial shows EMF triplet therapy is a safe, effective option for HNSCC, with CTCs serving as a promising biomarker for therapy response.

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ACO 2022 | Actorius Innovations and Research
Jun 7, 2022

ASCO 2022: Correlation of circulating tumor cells as a positive interventional biomarker in cancer patients

Ayurveda therapy significantly reduced CTC counts and improved quality of life in a study of 72 patients across 17 cancer types.

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Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer
Apr 27, 2022

Manuscript: Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer

Raj Shankar Hazra, Md Rakib Hasan Khan, Narendra Kale, Tabassum Tanha, Jayant Khandare, Sabha Ganai, and Mohiuddin Quadir*

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Antibody-coated cotton substrate for CTC enumeration and chemotherapy response.
Feb 18, 2022

Manuscript: Antibody mediated cotton-archetypal substrate for enumeration of circulating tumor cells and chemotherapy outcome in 3D tumors

Cotton microfluidic substrate enables efficient CTC isolation, 3D tumor growth, and drug response testing for improved cancer diagnostics and therapy research.

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ESMO 2021 | Actorius Innovations and Research
Oct 9, 2021

ESMO 2021: Validation of Cytokeratin (CK18) Protein Expression in Epithelial Cell lines and in Circulating Tumor Cells (CTCs)

Study shows significant CK18 expression variance across different cancer cell lines and CTCs, highlighting the need for regulated enumeration tools.

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ASCO 2021 | Actorius Innovations and Research
Jun 8, 2021

ASCO 2021: CTCs demonstrate a positive biomarker in head and neck squamous cell carcinoma (HNSCC) in tobacco consuming population of Bangladesh.

A study in Bangladesh found CTCs in 64% of HNSCC patients with chronic tobacco history, suggesting CTCs as a screening tool for early cancer detection.

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Actorius Patents
Apr 22, 2021

Multifunctional magneto-polymeric nanosystems for rapid targeting, isolation, detection and simultaneous imaging of circulating tumor cells

A multifunctional magneto-polymeric nanosystem for rapid targeting, isolation, detection, and imaging of circulating tumor cells to support cancer diagnostics and monitoring.

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Chemo-specific designs for the enumeration of CTCs: advances in liquid biopsy
Dec 18, 2020

Manuscript: Chemo-specific designs for the enumeration of circulating tumor cells: advances in liquid biopsy

Review on chemo-specific nano/micro substrates for efficient CTC isolation, enabling liquid biopsy, metastasis detection, and real-time cancer monitoring.

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Cellulose-based transferrin nanocages for CTC enumeration in head & neck cancer.
Oct 10, 2020

Manuscript: Cellulose Mediated Transferrin Nanocages for Enumeration of Circulating Tumor Cells for Head
and Neck Cancer

Magnetic transferrin-functionalized cellulose nanocages capture circulating tumor cells from blood, enabling liquid biopsy for early metastasis detection in head and neck cancer.

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OncoDiscover liquid biopsy enables CTC detection for cancer diagnosis and monitoring.
Aug 11, 2020

OncoDiscover Liquid Biopsy Technology | Clinical Significance of Circulating Tumor Cell Detection

Highlights the clinical value of circulating tumor cell detection using OncoDiscover liquid biopsy technology for cancer diagnosis and patient monitoring.

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Actorius Innovations and Research
Jul 15, 2020

ASCO 2020: Device for the enumeration and continuous removal of circulating tumor cells in improving
overall survival of epithelial cancer patients

The POP blood fluidic device safely removes CTCs with up to 100% efficiency, offering a new therapeutic path to reduce metastasis and improve survival.

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Times of India | Actorius Innovations and Research
Apr 23, 2020

Times of India | Liquid biopsy may replace invasive procedure to detect cancer: Experts

Liquid biopsy may replace invasive procedure to detect cancer: Experts

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